Preheat the oven to 375°F (190°C).
Place each chicken breast between two sheets of plastic wrap and gently pound with a meat mallet or rolling pin until about 1/4 inch thick.
In a small bowl, mix together the light cream cheese, garlic powder, onion powder, salt, and black pepper until well combined.
Spread an equal amount of the cream cheese mixture onto each flattened chicken breast.
Place about 1/2 cup of fresh spinach leaves evenly over the cream cheese layer on each chicken breast.
Carefully roll up each chicken breast tightly, starting from the narrow end, and secure with toothpicks if needed.
Heat olive oil in an oven-safe skillet over medium-high heat.
Place the chicken roll ups seam side down in the skillet and cook for 3-4 minutes until browned.
Turn the roll ups to brown all sides, about 2 minutes per side.
Sprinkle dried Italian seasoning over the chicken roll ups.
Transfer the skillet to the preheated oven and bake for 12-15 minutes, or until the chicken is cooked through and the internal temperature reaches 165°F (74°C).
Remove from oven and let rest for 5 minutes before removing toothpicks and slicing if desired.
Serve warm.