Preheat the air fryer to 375°F (190°C) for 5 minutes.
Pat the chicken breasts dry with paper towels.
In a small bowl, mix together salt, black pepper, garlic powder, and smoked paprika.
Rub the chicken breasts evenly with olive oil, then season both sides with the spice mixture.
Place the chicken breasts in the air fryer basket in a single layer, ensuring they do not overlap.
Cook the chicken breasts for 12 minutes, flipping halfway through the cooking time.
While the chicken is cooking, prepare the glaze by whisking together honey, Dijon mustard, apple cider vinegar, soy sauce, and crushed red pepper flakes in a small bowl.
After 12 minutes, brush the glaze generously over both sides of the chicken breasts.
Return the chicken to the air fryer and cook for an additional 3 minutes to set the glaze.
Remove the chicken from the air fryer and let it rest for 5 minutes before serving.